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Generic Estrace .01% Vaginal Cream, 42.5gm Tube (Prescription Product)

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With the availability of low dose generic Estrace, women experiencing symptoms of decreased estrogen have access to affordable treatment. Topical estradiol (generic Estrace) may be preferred over tablets due to quicker absorption and the immediate impact on vaginal lubrication, pain during sex, as well as itchiness in around the vagina. Your physician can determine if estradiol cream is right for you. If so, purchase FDA-approved generic Estrace and pay 40% less than the brands! .01% 42.5 gm tube with applicator. 

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Relief from hormonal imbalance is possible with estrogen cream

Low dose .01% estradiol vaginal cream is prescribed for Hormone Therapy (HT) to treat decreased estrogen levels in women at any age. 

Estradiol is the active ingredient in brand names Estrace, Vagifem, Yuvafem. Estradiol costs over 40% less than the brands and is FDA-approved generic equivalent. Estradiol is a naturally-occurring estrogen in the body. 

Why is estrogen important?

Estrogen's primary role in women is to regulate the reproductive system. When the body does not produce enough estrogen, related organs can decline and other health issues can develop.

Menopause is the first thought that comes to mind with reference to low estrogen but there are multiple other factors that influence estrogen. Common symptoms related to low estrogen are hot flashes, moodiness and night sweats.

What causes estrogen to decline?

Childbirth, stress, illness are shown to cause a drop in estrogen. As well, estrogen decline coincides with three major stages of the reproductive cycle: perimenopause, menopause and postmenopause.

Perimenopause are the 10 years leading up to menopause. Menopause is defined as the stage when a woman does not have her period for 12 consecutive months. Postmenopause are the years following.

Low dose estradiol is also prescribed for lesser discussed conditions. Atrophic Vaginitis (vaginal atrophy) can occur at any time during a woman's life. Symptoms of vaginal atrophy are pain during sex, vaginal dryness accompanied by itching and burning in and around the vagina. 

Genitourinary Syndrome of Menopause (GSM) is specific to postmenopausal women. It can lead to thinning of the urethra lining and pelvic floor. Repeated urinary tract infections, frequent urination, the sudden urge to urinate and some incontinence are among the symptoms of GSM. 

Besides menopause, why else is estrogen prescribed?

  •     Osteoporosis prevention
  •     Ovarian failure
  •     Specific cancer treatment
  •     Feminizing hormone therapy

Available as a topical cream, estradiol (generic Estrace), is quickly absorbed into the body and capable of increasing estrogen levels within minutes, reaching the peak delivery in half an hour.1 Relief from estradiol may begin 1-2 weeks after continued use. Full benefits may take 3-4 weeks. 

Don't miss out. Ask if generic Estrace topical vaginal cream is right for you!

To ensure that we provide you with the best price, we may substitute one generic for another. 

1"Systemic Effects of Vaginally Administered Estrogen Therapy: A Review" From Last visited Nov. 8, 2018

More Information
Is a Prescription Product Yes
Use or Effects Hormonal Therapy, Relieve Menopause Symptoms, Relieve Pain During Sex, Treat Vaginal Dryness
Form Cream
Drug Class/Pharmacology Hormone
Product Specifics

Estradiol vaginal cream 0.01% is indicated in the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause.

Estradiol vaginal cream 0.01% should not be used in women with any of the following conditions:

  • Undiagnosed abnormal genital bleeding.
  • Known, suspected, or history of cancer of the breast. 
  • Known or suspected estrogen-dependent neoplasia. 
  • Active DVT, PE or history of these conditions.
  • Active arterial thromboembolic disease (for example, stroke, MI) or a history of these conditions. 
  • Known anaphylactic reaction or angioedema to estradiol vaginal cream 0.01%. 
  • Known liver dysfunction or disease. 
  • Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders.
  • Known or suspected pregnancy
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